myxoid soft tissue tumors
Wednesday 10 April 2013
soft tissue myxoid tumors; myxoid tumors of soft tissues; myxoid lesions of soft tissue; soft tissue myxoid tumors; myxoid tumours of soft tissue
Definition: Myxoid tumours of soft tissue encompass a heterogeneous group of lesions characterized by a marked abundance of extracellular mucoid (myxoid) matrix.
Circumscribed myxoid lesion of finger by Ed Euthman
Ossifying fibromyxoid tumour, male, 60yo, right thigh
This group of tumours demonstrate significant variability in their biological behaviour thus including tumours which are entirely harmless, tumours with a tendency to recur locally but not metastasize, and malignant tumours.
There appears to be a considerable degree of overlap clinically and morphologically between the various tumour types in this group, generating potential diagnostic problems for the clinician and pathologist alike.
While diligent microscopy remains the basis of diagnostic pathology, the continuous developments and refinements within the fields of immunohistochemistry and molecular cytogenetics are providing substantial new information, allowing the development of new diagnostic criteria and hence facilitating an accurate diagnosis.
|Dermal myxoma||Juxta-articular myxoma||Myxofibrosarcoma|
|Superficial angiomyxoma||Aggressive angiomyxoma||Low-grade fibromyxoid sarcoma|
|Ganglion||(Low-grade myxofibrosarcoma)||Myxoid liposarcoma|
|Myxoid nodular fasciitis||(Atypical OFMT)||Extraskeletal myxoid chondrosarcoma|
|Myxoid neurofibroma||Myxoid leiomyosarcoma|
|Dermal nerve sheath myxoma||Myxoid DFSP|
|Intramuscular myxoma||Myxopapillary ependymoma|
|Ossifying fibromyxoid tumour (OFMT)|
myxoid fibroblastic sarcoma
Myxoid tumours of soft tissue. Graadt van Roggen JF, Hogendoorn PC, Fletcher CD. Histopathology. 1999 Oct;35(4):291-312. PMID: 10564384 http://www.pathologydiagnostics.org/userfiles/Myxoid_tumours.pdf