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pulmonary pleomorphic carcinoma

Monday 18 March 2013

Pleomorphic carcinoma of the lung

Pleomorphic carcinoma (PC) of the lung is rare, and it is classified as a subtype of sarcomatoid carcinoma of the lung in the World Health Organization histologic classification of lung tumors.

When the PC patients are divided into 3 groups according to the predominant epithelial component, an adenocarcinoma group, squamous cell carcinoma group, and large cell carcinoma group, there were no significant differences in the overall survival rate and median survival time between the 3 groups.

PC should be considered as an aggressive disease and massive necrosis should be routinely reported and used as a factor in clinical assessments.

References

- Pleomorphic carcinoma of the lung: clinicopathologic characteristics of 70 cases. Mochizuki T, Ishii G, Nagai K, Yoshida J, Nishimura M, Mizuno T, Yokose T, Suzuki K, Ochiai A. Am J Surg Pathol. 2008 Nov;32(11):1727-35. doi : 10.1097/PAS.0b013e3181804302 PMID: 18769330