IgG4-associated pleural disease
Friday 4 January 2013
IgG4-related lung and pleural disease
Pleura is severely thickened by diffuse sclerosing inflammation.
Fibrosis is more pronounced on the side of the pleural cavity.
In the parietal lesion, sclerosing inflammation extends into subpleural fibrous and adipose tissue.
Visceral pleural lesions severely involve subpleural lung parenchyma.
Those parenchymal lesions resembled the solid nodular type.
IgG4-related lung and pleural disease: a clinicopathologic study of 21 cases. Zen Y, Inoue D, Kitao A, Onodera M, Abo H, Miyayama S, Gabata T, Matsui O, Nakanuma Y. Am J Surg Pathol. 2009 Dec;33(12):1886-93. doi : 10.1097/PAS.0b013e3181bd535b PMID: 19898222
Lung involvement in IgG4-related lymphoplasmacytic vasculitis and interstitial fibrosis: report of 3 cases and review of the literature. Yamashita K, Haga H, Kobashi Y, Miyagawa-Hayashino A, Yoshizawa A, Manabe T. Am J Surg Pathol. 2008 Nov;32(11):1620-6. doi : 10.1097/PAS.0b013e318172622f PMID: 18753944