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eccrine syringofibroadenomae

Sunday 8 November 2020

eccrine syringofibroadenoma (of Mascaro), acrosyringeal adenomatosis
Eccrine poromatosis
Linear eccrine poroma
Acrosyringeal nevus of Weedon and Lewis
Nevus syringoadenomatosus papilliferum


Definition : A rare benign eccrine proliferation with anastomosing cords in a fibrovascular stroma.


- anastomoting strands of epithelial cells
- anastomosing reticulated cords and strands of basaloid monomorphous cuboidal cells extending from the basal layer of epidermis into dermis
- cells are slightly smaller than neighboring keratinocytes
- loose fibrovascular stroma
- cords have scattered ductal structures resembling eccrine ducts lined by CEA+ cells
- +/- nests of clear cells

Differential diagnosis

- acrosyringeal nevus
- clear cell acanthoma
- CBC : fibroepithelioma of Pinkus
- poroma
- porocarcinoma