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Nuclear grooving

Thursday 1 November 2012

Nuclear groove, Nuclear grooves

Tumor types

- papillary thyroid carcinoma

  • Nuclear grooving is a useful morphologic feature in the diagnosis of papillary carcinoma of the thyroid (PTC) in tissue sections and imprint smears.
  • Nuclear grooving, when seen in abundance, can be considered a reliable criterion for the diagnosis of papillary carcinoma in fine needle aspiration cytology of the thyroid.
  • The presence of occasional grooves, however, should be regarded as a nonspecific finding.

- Langerahns histiocytosis

See also

- PMID: 2916367