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pulmonary giant cell carcinoma

Thursday 4 October 2012

Giant-cell carcinoma of the lung

WP

Digital cases

- JRC:6222 : pulmonary giant cell carcinoma.
- JRC:6223 : pulmonary giant cell carcinoma.
- JRC:6224 : pulmonary giant cell carcinoma.

Definition: Giant cell carcinoma of the lung (GCCL) is a rare histological form of undifferentiated lung cancer traditionally classified within the non-small cell lung carcinomas (NSCLC).

The characteristic feature of this highly lethal malignancy is the distinctive light microscopic appearance of its extremely large cells, which are bizarre and highly pleomorphic, and which often contain more than one huge, misshapen, pleomorphic nucleus ("syncytia"), which result from cell fusion.

See also

- pulmonary carcinomas