pulmonary giant cell carcinoma
Thursday 4 October 2012
Giant-cell carcinoma of the lung
Definition: Giant cell carcinoma of the lung (GCCL) is a rare histological form of undifferentiated lung cancer traditionally classified within the non-small cell lung carcinomas (NSCLC).
The characteristic feature of this highly lethal malignancy is the distinctive light microscopic appearance of its extremely large cells, which are bizarre and highly pleomorphic, and which often contain more than one huge, misshapen, pleomorphic nucleus ("syncytia"), which result from cell fusion.