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Home > B. Cellular pathology > clefted nuclei

clefted nuclei

Sunday 30 September 2012

cells with longitudinal nuclear grooves; coffee bean nuclei

See also : nuclear grooves


- papillary thyroid carcinoma (PTC)

- granulosa cell tumor

  • Granulosa cell tumor has sheets of small cells with longitudinal nuclear grooves (“ coffee bean nuclei ”), and Call-Exner bodies (eosinophilic fluid filled spaces surrounded by granulosa cells). Most tumors cause hyperestrogenism.

- Brenner tumor / Brenner cell tumor

- Deeply clefted nuclei suspect follicular lymphoma t(14;18)(q32;q21)

See also

- nuclear anomalies