Home > G. Tumoral pathology > Cancer molecular profiling > Amplifications > Gene amplications > EGFR amplification

EGFR amplification

Friday 14 September 2012

Pathology

- Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas. (22472960)

References

- Concurrence of EGFR amplification and sensitizing mutations indicate a better survival benefit from EGFR-TKI therapy in lung adenocarcinoma patients. Shan L, Wang Z, Guo L, Sun H, Qiu T, Ling Y, Li W, Li L, Liu X, Zheng B, Lu N, Ying J. Lung Cancer. 2015 Jun 19. pii: S0169-5002(15)00293-7. doi : 10.1016/j.lungcan.2015.06.008 PMID: 26141217

- Paradoxical relationship between the degree of EGFR amplification and outcome in glioblastomas. Hobbs J, Nikiforova MN, Fardo DW, Bortoluzzi S, Cieply K, Hamilton RL, Horbinski C. Am J Surg Pathol. 2012 Aug;36(8):1186-93. PMID: 22472960