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clear cell cribriform hyperplasia

Thursday 30 August 2012

Prostate Clear Cell Cribriform Hyperplasia; prostatic clear cell cribriform hyperplasia; CCCH


The cells of CCCH are cytologically benign, they lack prominent nucleoli and do not have an increased N/C ratio. The lesion shows a basal cell layer and papillary growth of glands with clear to eosinophilic cells with prominent cribriforming.


- Lobular clusters of glands with cribriform architecture.
- The glandular clusters have punched out lumens.
- The cytoplasm is clear or pale eosinophilic.
- The nuclei are uniform and lack nucleoli.
- Basal cells can be clearly seen.

See also

- prostatic epithelial anomalies