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chronic myelomonocytic leukemia

Monday 27 August 2012

Chronic myelomonocytic leukemia (CMML) is a rare clonal hematopoietic disorder.

Cutaneous CMML tumors

Chronic myelomonocytic leukemia (CMML) can also involve the skin.

A minimal panel of immunohistochemical markers including CD68, CD1a, S100, Langerin, and CD123 is necessary to make the correct classification in this spectrum of cutaneous CMML tumors, in which dendritic cell lineage plays an important role.

Reference

- Specific Skin Lesions in Chronic Myelomonocytic Leukemia: A Spectrum of Myelomonocytic and Dendritic Cell Proliferations. A Study of 42 Cases. Vitte F, Fabiani B, BĂ©net C, Dalac S, Balme B, Delattre C, Vergier B, Beylot-Barry M, Vignon-Pennamen D, Ortonne N, Algros MP, Carlotti A, Samaleire D, Frouin E, Levy A, Laroche L, Theate I, Monnien F, Mugneret F, Petrella T. Am J Surg Pathol. 2012 Sep;36(9):1302-1316. PMID: #22895265#