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CD3-expressing B-cell lymphoma

Monday 27 August 2012

B-Cell Lineage Neoplasms With Aberrant Expression of CD3

CD3 expression by immunohistochemistry was historically considered restricted to T-lineage or NK-lineage neoplasms but recently has been reported in rare cases of mature B-cell neoplasms, frequently in association with Epstein-Barr virus.

Reference

- Clinicopathologic Features of B-Cell Lineage Neoplasms With Aberrant Expression of CD3: A Study of 21 Cases. Oliveira JL, Grogg KL, Macon WR, Dogan A, Feldman AL. Am J Surg Pathol. 2012 Sep;36(9):1364-70. PMID: #22895269#