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pouch and peripouch adenocarcinoma

Monday 27 August 2012

pouch adenocarcinoma; peripouch adenocarcinoma

The occurrence of adenocarcinoma after ileal pouch-anal anastomosis for ulcerative colitis (UC) is an infrequent but potentially lethal complication.

Pouch and peripouch adenocarcinoma can occur in patients without colorectal neoplasia and in those with idiopathic inflammatory bowel disease, can be potentially lethal, and has histomorphologic and molecular features similar to those of UC-associated adenocarcinoma.

Reference

- Histomorphologic and Molecular Features of Pouch and Peripouch Adenocarcinoma: A Comparison With Ulcerative Colitis-associated Adenocarcinoma. Jiang W, Shadrach B, Carver P, Goldblum JR, Shen B, Liu X. Am J Surg Pathol. 2012 Sep;36(9):1385-94. PMID: 22895272