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collagenous micronodules

Tuesday 31 July 2012

See also : mucinous fibroplasia

The delicate ingrowth of fibrous tissue seen with mucinous fibroplasia can result in glands appearing to be fused resembling cribriform structures although the underlying architecture is really that of individual discrete rounded glands invested by loose collagen.

The tumor should be graded on the underlying glandular architecture, whereby the majority are graded as Gleason score 3+3=6.

Only when there are distinct cribriform glands in areas of mucinous fibroplasias does this author diagnose Gleason pattern 4.

See also

- micronodules