Saturday 22 November 2003
UI:254 - Atherosclerosis - recanalization
UI:390 - Atherosclerosis with fatty streak
UI:614 - Atherosclerosis: Cholesterol clefts
UI:677 - Atherosclerosis: Cholesterol clefts and dystrophic calcifiction
UI:716: Thrombus on Atherosclerotic plaque
Definition: Atherosclerosis is a ’narrowing’ or hardening of the arteries by fibrosis of the vascular wall caused by atheroma.
Itis a pathological process that involves the progressive expansion of lesions (plaques) that reduce blood flow in arteries.
Atherosclerosis is a condition in which an artery wall thickens as a result of the accumulation of fatty materials such as cholesterol.
It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries, caused largely by the accumulation of macrophage white blood cells and promoted by low-density lipoproteins (LDL, plasma proteins that carry cholesterol and triglycerides) without adequate removal of fats and cholesterol from the macrophages by functional high-density lipoproteins (HDL), (see apoA-1 Milano).
It is commonly referred to as a hardening or furring of the arteries. It is caused by the formation of multiple plaques within the arteries.
arteriosclerosis (also known as arteriosclerotic vascular disease or ASVD)
de Nigris F, Lerman A, Ignarro LJ, Williams-Ignarro S, Sica V, Baker AH, Lerman LO, Geng YJ, Napoli C. Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis. Trends Mol Med. 2003 Aug;9(8):351-9. PMID: 12928037