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Saturday 21 April 2012



A103 is a melanocyte-associated monoclonal antibody that recognizes the Melan-A/MART-1 antigen (MLNA) in melanomas.

Expression in tumors

- melanoma
- sex cord stromal tumors of the ovary (SCSTs) (12966351)
- adrenal cortical tumors (12808065)

  • adrenal cortical carcinoma

- angiomyolipoma


- Yan S, Brennick JB. False-positive Rate of the Immunoperoxidase Stains for MART1/MelanA in Lymph Nodes. Am J Surg Pathol. 2004 May;28(5):596-600. PMID: 15105646

- A103: An anti-melan-a monoclonal antibody for the detection of malignant melanoma in paraffin-embedded tissues. Jungbluth AA, Busam KJ, Gerald WL, Stockert E, Coplan KA, Iversen K, MacGregor DP, Old LJ, Chen YT. Am J Surg Pathol. 1998 May;22(5):595-602. PMID: 9591730

- Busam KJ, Iversen K, Coplan KA, Old LJ, Stockert E, Chen YT, McGregor D, Jungbluth A. Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors. Am J Surg Pathol. 1998 Jan;22(1):57-63. PMID: 9422316