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MYD88

Tuesday 10 April 2012

Mutations

- MYD88-p.L265P

  • Activation of TAK1 by MYD88 L265P drives malignant B-cell Growth in non-Hodgkin lymphoma. #24531446#
  • MYD88 L265P somatic mutation in Waldenström’s macroglobulinemia. #22931316#, #23532735#, #23723443#
    • L265P mutation of the MYD88 gene is frequent in Waldenström’s macroglobulinemia and its absence in myeloma. #24224040#
    • MYD88 L265P mutations are correlated with 6q deletion in korean patients with Waldenström macroglobulinemia. #24895570#
  • CD79B and MYD88 Mutations in Splenic Marginal Zone Lymphoma. #23378931#
  • Gamma heavy chain disease lacks the MYD88 l265p mutation associated with lymphoplasmacytic lymphoma. #24859878#
  • MYD88 -p.L265P mutation is associated with lymphoplasmacytic lymphoma. #24859878#

See also

- Toll-like receptor pathways

Portfolio

  • Toll-like receptor pathways