Friday 23 March 2012
Angioleiomyomas of the Dura
Angioleiomyomas (ALMs) are cutaneous and soft tissue lesions usually seen in the lower extremities of middle-aged women.
The lesions are nodular, mulberry like, and composed of vessels of varying size with abundant intervening smooth muscle; an arterial component is absent.
Intracranial examples are exceedingly rare, with <10 cases reported to date, and are usually dural in location.
Dural ALMs are easily clinically mistaken for CCMs or meningiomas but are not of similar histopathogenesis.
Angioleiomyomas of the Dura: Rare Entities That Lack KRIT1 Mutations. Conner TM, Waziri A, Kleinschmidt-Demasters BK. Am J Surg Pathol. 2012 Apr;36(4):526-33. PMID: #22261708#