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dural angioleiomyoma

Friday 23 March 2012

Angioleiomyomas of the Dura

Angioleiomyomas (ALMs) are cutaneous and soft tissue lesions usually seen in the lower extremities of middle-aged women.

The lesions are nodular, mulberry like, and composed of vessels of varying size with abundant intervening smooth muscle; an arterial component is absent.

Intracranial examples are exceedingly rare, with <10 cases reported to date, and are usually dural in location.

Dural ALMs are easily clinically mistaken for CCMs or meningiomas but are not of similar histopathogenesis.

References

- Angioleiomyomas of the Dura: Rare Entities That Lack KRIT1 Mutations. Conner TM, Waziri A, Kleinschmidt-Demasters BK. Am J Surg Pathol. 2012 Apr;36(4):526-33. PMID: #22261708#