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mismatch repair immunochemistry

Friday 23 March 2012

MMR immunochemistry

The mismatch repair (MMR) status of tumors is being increasingly recognized as a prognostic, predictive, and possible germline predisposition/Lynch syndrome (LS) biomarker in colorectal cancer and other cancer types, particularly in endometrial cancer.

References

- Use of mismatch repair immunohistochemistry and microsatellite instability testing: exploring canadian practices. Kalloger SE, Allo G, Mulligan AM, Pollett A, Aronson M, Gallinger S, Torlakovic EE, Clarke BA. Am J Surg Pathol. 2012 Apr;36(4):560-9. PMID: 22301492