NUT-associated pulmonary carcinoma
Friday 23 March 2012
pulmonary NUT midline carcinoma, pulmonary NUT-associated midline carcinoma, pulmonary NUT-associated carcinoma
These tumors are diffusely positive for p63 and NUT expression and are partially positive for various cytokeratins.
Reverse transcription polymerase chain reaction analysis and subsequent direct sequencing reveal that the bromodomain-containing protein 4-NUT chimeric gene is present in tumor tissue of both patients, leading to a diagnosis of NMC.
- NUT-associated midline carcinoma
NUT Midline Carcinoma: Report of 2 Cases Suggestive of Pulmonary Origin. Tanaka M, Kato K, Gomi K, Yoshida M, Niwa T, Aida N, Kigasawa H, Ohama Y, Tanaka Y. Am J Surg Pathol. 2012 Mar;36(3):381-8. PMID: 22301500