composite adrenal medullary tumor
Friday 2 March 2012
composite adrenal medullary neoplasms; Composite adrenal pheochromocytoma; composite adrenal medullary tumors
Little is known about its biologic potential, therefore creating a clinical dilemma on diagnosis.
Composite pheochromocytoma may be regarded as a histologic variant of classic pheochromocytoma.
Most of these tumors have been reported in adults, but have been infre-quently observed in children.
Composite pheochromocytoma: a clinicopathologic and molecular comparison with ordinary pheochromocytoma and neuroblastoma. Comstock JM, Willmore-Payne C, Holden JA, Coffin CM. Am J Clin Pathol. 2009 Jul;132(1):69-73. PMID: 19864235
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Aiba M, Hirayama A, Ito Y, et al. A compound adrenal medullary tumor (pheochromocytoma and ganglioneuroma) and a cortical adenoma in the ipsilateral adrenal gland: a case report with enzyme histochemical and immunohistochemical studies. Am J Surg Pathol. 1988;12:559-566.
Balazs M. Mixed pheochromocytoma and ganglioneuroma of the adrenal medulla: a case report with electron microscopic examination. Hum Pathol. 1988;19:1352-1355.
Brady S, Lechan RM, Schwaitzberg SD, et al. Composite pheochromocytoma/ganglioneuroma of the adrenal gland associated with multiple endocrine neoplasia 2A: case report with immunohistochemical analysis. Am J Surg Pathol. 1997;21:102-108.
Kragel PJ, Johnston CA. Pheochromocytoma-ganglioneuroma of the adrenal. Arch Pathol Lab Med. 1985;109:470-472.