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adrenal cortical tumors
Friday 2 March 2012
adrenocortical tumors
Digital cases
JRC:14604 : Adrenal cortical adenoma. JRC:14612 : Atypical adrenal cortical adenoma. JRC:14613 : Adrenal cortical carcinoma (with Cushing syndrome) JRC:18771 : Adrenal carcinoma (NOS) JRC:18772 : Adrenal adenoma (NOS).
Types according to grade
adrenocortical adenoma (adrenal cortical adenoma) adrenocortical carcinoma (adrenal cortical carcinoma)
Types according to secretion
non-secreting adrenocortical tumor androgens-secreting adrenocortical tumor aldosterone-secreting adrenocortical tumor cortisol-secreting adrenocortical tumor
Types according to age
pediatric adrenal cortical tumors
LOH
17q22-24 LOH (PRKAR1A locus) (#14500362#)
Gene mutations
somatic mutations in the PRKAR1A gene (#14500362#)
References
Adrenocortical Tumors: Improving the Practice of the Weiss System Through Virtual Microscopy: A National Program of the French Network INCa-COMETE. Tissier F, Aubert S, Leteurtre E, Al Ghuzlan A, Patey M, Decaussin M, Doucet L, Gobet F, Hoang C, Mazerolles C, Monges G, Renaudin K, Sturm N, Trouette H, Vacher-Lavenu MC, Viallon V, Baudin E, Bertagna X, Coste J, Libe R. Am J Surg Pathol. 2012 Aug;36(8):1194-1201. PMID: #22790860#
