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presenilin-1

Friday 21 November 2003

Features

- Notch signaling pathway

References

- Martoglio B, Golde TE. Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R201-6. Epub 2003 Sep 09. PMID: 12966028

- Van Gassen G, Annaert W. Amyloid, presenilins, and Alzheimer’s disease.
Neuroscientist. 2003 Apr;9(2):117-26. PMID: 12708616

- Tandon A, Fraser P. The presenilins. Genome Biol. 2002 Oct 23;3(11):reviews3014. PMID: 12429067

- Fortini ME. Notch and presenilin: a proteolytic mechanism emerges. Curr Opin Cell Biol. 2001 Oct;13(5):627-34. PMID: 11544033

- Steiner H, Haass C. Intramembrane proteolysis by presenilins. Nat Rev Mol Cell Biol. 2000 Dec;1(3):217-24. PMID: 11252897

- Theuns J, Van Broeckhoven C. Transcriptional regulation of Alzheimer’s disease genes: implications for susceptibility. Hum Mol Genet. 2000 Oct;9(16):2383-94. PMID: 11005793

- Sisodia SS, Kim SH, Thinakaran G. Function and dysfunction of the presenilins. Am J Hum Genet. 1999 Jul;65(1):7-12. PMID: 10364510