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SNPs

Friday 21 November 2003

Not all nucleotide changes produce genes that cause disease. When such a DNA change occurs in at least 1% of the population, it is called a polymorphism. SNPs is the most common form of polymorphism.

See also

- SNPs microarrays
- STRs

Links

- Seatlle SNPs
- Genes Sequenced for SNPs at Seatlle SNPs

References

- Population genetics: SNPs that come in threes. Casci T. Nat Rev Genet. 2010 Jan;11(1):8. PMID: #20050277#

- Payseur BA, Cutter AD. Integrating patterns of polymorphism at SNPs and STRs. Trends Genet. 2006 Aug;22(8):424-9. PMID: #16806567#

- Lee C. Irresistible force meets immovable object: SNP mapping of complex diseases. Trends Genet. 2002 Feb;18(2):67-9. PMID: #11818133#

- Wakeley J, Nielsen R, Liu-Cordero SN, Ardlie K. The discovery of single-nucleotide polymorphisms—and inferences about human demographic history. Am J Hum Genet. 2001 Dec;69(6):1332-47. PMID: #11704929#

- Gray IC, Campbell DA, Spurr NK. Single nucleotide polymorphisms as tools in human genetics. Hum Mol Genet. 2000 Oct;9(16):2403-8. PMID: #11005795#

- Shen, L. X.; Basilion, J. P.; Stanton, V. P., Jr. : Single-nucleotide polymorphisms can cause different structural folds of mRNA. Proc. Nat. Acad. Sci. 96: 7871-7876, 1999. PubMed ID : #10393914#