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von Hippel-Lindau disease

Thursday 20 November 2003

Synopsis

- VHL-associated pulmonary anomalies (17667557)

- VHL-associated pancreatic anomalies

  • VHL-associated pancreatic cysts

- VHL-associated renal anomalies

  • VHL-associated renal cell carcinoma
    • VHL-associated cystic renal cell carcinoma

Reviews

- Maher ER. Von Hippel-Lindau disease. Curr Mol Med. 2004 Dec;4(8):833-42. PMID: #15579030

- Barry RE, Krek W. The von Hippel-Lindau tumour suppressor: a multi-faceted inhibitor of tumourigenesis. Trends Mol Med. 2004 Sep;10(9):466-72. PMID: 15350900

- George DJ, Kaelin WG Jr. The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer. N Engl J Med. 2003 Jul 31;349(5):419-21. PMID: 12890838

- Kaelin WG Jr. Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer. 2002 Sep;2(9):673-82. PMID: 12209156

- Kaelin WG Jr, Maher ER. The VHL tumour-suppressor gene paradigm. Trends Genet. 1998 Oct;14(10):423-6. PMID: 9820032

- Friedrich CA. Genotype-phenotype correlation in von Hippel-Lindau syndrome. Hum Mol Genet. 2001 Apr;10(7):763-7. PMID: 11257110

References

- Klein J, Zhuang Z, Lubensky I, Colby TV, Martinez F Jr, Leslie KO. Multifocal microcysts and papillary cystadenoma of the lung in von Hippel-Lindau disease. Am J Surg Pathol. 2007 Aug;31(8):1292-6. PMID: 17667557

Portfolio

  • VHL-associated cystic renal cell carcinoma