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in situ urothelial carcinoma

Saturday 11 February 2012

urothelial Cis;Urothelial Carcinoma-in-situ

Digital cases

- UI:513 : Urothelial carcinoma (transitional cell carcinoma) in-situ

Images

- http://www.webpathology.com/image.asp?n=7&Case=57

Definition: Urothelial dysplasia and carcinoma in situ (CIS) are related to recurrence and progression of urothelial carcinoma.

Types

- papillary urothelial anomalies
- flat urothelial anomalies

Differential diagnosis

- urothelial reactive atypia

See also

- urothelial carcinoma (transitional cell carcinoma)

Open References

- Immunohistochemical expression of CK20, p53, and Ki-67 as objective markers of urothelial dysplasia. MallofrĂ© C, Castillo M, Morente V, SolĂ© M.
Mod Pathol. 2003 Mar;16(3):187-91.
PMID: 12640096 (free)
http://www.nature.com/modpathol/journal/v16/n3/full/3880741a.html

References

- Discriminatory immunohistochemical staining of urothelial carcinoma in situ and non-neoplastic urothelium: an analysis of cytokeratin 20, p53, and CD44 antigens.
McKenney JK, Desai S, Cohen C, Amin MB.
Am J Surg Pathol. 2001 Aug;25(8):1074-8.
PMID: 11474293