multifocal urothelial carcinoma
Thursday 8 December 2011
There is a clonal relationship between different synchronous bladder tumors but also show that the intratumor heterogeneity present in different subpopulations of the same tumor reproduces the behavior of independent synchronous tumors in a same patient.
Genomic imbalances in urothelial cancer: intratumor heterogeneity versus multifocality. Prat E, Del Rey J, Camps J, Ponsa I, Lloreta J, Egozcue J, Gelabert A, Campillo M, Miro R. Diagn Mol Pathol. 2008 Sep;17(3):134-40. PMID: 18382360