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cell surface capturing

Wednesday 26 October 2011

The molecular composition and dynamic organization of the plasma membrane (PM) determine how a cell can interact with its environment at any given moment.

Cell surface proteins are crucial for cell-cell communication, interaction with pathogens, binding of chemical messengers, and responding to environmental perturbations.

Alterations in the PM protein composition, as a result of a disease may well define phenotypic and functional differences between normal, and for example, tumor cells.

Cell surface proteins can be markers of disease and are potential targets for pharmaceutical intervention.