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bilateral testicular Sertoli cell tumors

Friday 21 October 2011

Large cell calcifying Sertoli cell tumor of the testicle is a rare, hormonally active sex cord-stromal tumor seen in patients with Carney complex.

When such tumors occur bilaterally, treatment options for preserving fertility and addressing the secondary effects of excess hormone production must be considered.

The availability of specific antiestrogen drugs means that bilateral orchiectomy for this benign tumor may no longer be warranted.

Testicular-sparing surgery and advances in reproductive technology may also improve the overall prognosis for fertility.

Gynecomastia in prepubescent boys can be emotionally very distressing.


- Conservative management of bilateral Sertoli cell tumors of the testicle in association with the Carney complex: a case report. Brown B, Ram A, Clayton P, Humphrey G. J Pediatr Surg. 2007 Sep;42(9):E13-5. PMID: 17848226