Tuesday 21 June 2011
UI: - Rickets
Rickets is a disordered overgrowth of epiphyseal cartilage, a characteristic of Rickets.
Cartilage at the osteochondral junction fails to mature, disintegrate, and mineralize.
Instead, it forms a laterally expanding mass.
When osteoid is deposited on insufficiently mineralized cartilage, the result is weak bone that fractures easily.
The presence of microfractures cause overgrowth of fibroblasts and capillaries in this area.