Home > Technical section > Biology > Molecular biology > Genomics > cancer whole-genome sequencing

cancer whole-genome sequencing

Sunday 17 April 2011

cancer WGS, WCGS, oncogenome, whole cancer genome sequencing; cancer genome sequencing, oncogenome sequencing

Videos

Comparison of primary and metastatic acral melanoma by whole genome sequencing

Video: Greg Tyrelle - Complete Genomics - Whole Oncogenome Sequencing: Is tomorrow today?

See also

- cancer exome sequencing

Reviews

- Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing. Leary RJ, Sausen M, Kinde I, Papadopoulos N, Carpten JD, Craig D, O’Shaughnessy J, Kinzler KW, Parmigiani G, Vogelstein B, Diaz LA Jr, Velculescu VE. Sci Transl Med. 2012 Nov 28;4(162):162ra154. doi: 10.1126/scitranslmed.3004742 . PMID: #23197571#

- Whole cancer genome sequencing by next-generation methods. Ross JS, Cronin M. Am J Clin Pathol. 2011 Oct;136(4):527-39. PMID: #21917674#

- Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology. Cronin M, Ross JS. Biomark Med. 2011 Jun;5(3):293-305. Review. PMID: #21657839#

- Advances in understanding cancer genomes through second-generation sequencing. Meyerson M, Gabriel S, Getz G. Nat Rev Genet. 2010 Oct;11(10):685-96. PMID: #20847746#

References

- Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Fujimoto A, Totoki Y, Abe T, Boroevich KA et al. Nat Genet. 2012 May 27;44(7):760-4. doi: 10.1038/ng.2291.PMID: #22634756#

- Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Molenaar JJ, Koster J, Zwijnenburg DA, van Sluis P, Valentijn LJ, van der Ploeg I, Hamdi M, van Nes J, Westerman BA, van Arkel J, Ebus ME, Haneveld F, Lakeman A, Schild L, Molenaar P, Stroeken P, van Noesel MM, Ora I, Santo EE, Caron HN, Westerhout EM, Versteeg R. Nature. 2012 Feb 22;483(7391):589-93. doi: 10.1038/nature10910. PMID: #22367537#

- Whole-genome reconstruction and mutational signatures in gastric cancer. Nagarajan N, Bertrand D, Hillmer AM, Zang ZJ et al. Genome Biol. 2012 Dec 13;13(12):R115. PMID: #23237666#

- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Puente XS, Pinyol M, Quesada V et al. Nature. 2011 Jun 5;475(7354):101-5. PMID: #21642962#