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epithelioid hemangioendothelioma of soft tissues - Humpath.com - Human pathology

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epithelioid hemangioendothelioma of soft tissues

Friday 8 April 2011

Definition: Epithelioid hemangioendothelioma (EHE) of soft tissue is a distinctive vascular tumor that has been variously considered a tumor of borderline malignancy and low-grade angiosarcoma. The majority of cases are associated with low mortality, but some metastasize and cause patient death.

EHE can be stratified into 2 risk groups with markedly different clinical courses. Patients with high-risk tumors had a 5-year disease-specific survival of 59%; no patients with low-risk tumors died. (18551749)

References

- Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Deyrup AT, Tighiouart M, Montag AG, Weiss SW. Am J Surg Pathol. 2008 Jun;32(6):924-7. PMID: 18551749