epithelioid hemangioendothelioma of soft tissues
Friday 8 April 2011
Definition: Epithelioid hemangioendothelioma (EHE) of soft tissue is a distinctive vascular tumor that has been variously considered a tumor of borderline malignancy and low-grade angiosarcoma. The majority of cases are associated with low mortality, but some metastasize and cause patient death.
EHE can be stratified into 2 risk groups with markedly different clinical courses. Patients with high-risk tumors had a 5-year disease-specific survival of 59%; no patients with low-risk tumors died. (18551749)
Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Deyrup AT, Tighiouart M, Montag AG, Weiss SW. Am J Surg Pathol. 2008 Jun;32(6):924-7. PMID: 18551749