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invasive ampullary adenocarcinoma

Tuesday 30 November 2010

Tumor budding is frequently encountered in AAC. High-budding is a strong independent predictor of overall survival, with a prognostic correlation stronger than the 2 established parameters: T-stage and lymph node metastasis.

Therefore, budding should be incorporated into surgical pathology reports for AAC.


- Tumor budding as a strong prognostic indicator in invasive ampullary adenocarcinomas. Ohike N, Coban I, Kim GE, Basturk O, Tajiri T, Krasinskas A, Bandyopadhyay S, Morohoshi T, Shimada Y, Kooby DA, Staley CA, Goodman M, Volkan Adsay N. Am J Surg Pathol. 2010 Oct;34(10):1417-24. (20871215)