Wednesday 6 October 2010
Expression of the T-SP1 protein was found in the Leydig and Sertoli cells of the testis and in the epithelial cells of the ductuli efferentes.
Notably, T-SP1 protein was also detectable in prostate cancer and in some ovarian cancer tissues, indicating tumor-related synthesis of T-SP1 beyond testis tissue.
T-SP1: a novel serine protease-like protein predominantly expressed in testis. Neth P, Profanter B, Geissler C, Nägler DK, Nerlich A, Sommerhoff CP, Jochum M. Biol Chem. 2008 Dec;389(12):1495-504. PMID: 18844450