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p16+ oropharyngeal squamous cell carcinoma

Tuesday 7 September 2010

Outcomes for p16 positive, HPV negative oropharyngeal SCC are not significantly different from p16 positive, HPV positive tumors and are significantly better than for p16 negative tumors. (20588174)

These results suggest that p16 immunohistochemistry alone is the best test to use for risk stratification in oropharyngeal SCC.

See also

- oropharyngeal squamous cell carcinoma

  • HPV-associated oropharyngeal squamous cell carcinoma


- p16 positive oropharyngeal squamous cell carcinoma:an entity with a favorable prognosis regardless of tumor HPV status. Lewis JS Jr, Thorstad WL, Chernock RD, Haughey BH, Yip JH, Zhang Q, El-Mofty SK. Am J Surg Pathol. 2010 Aug;34(8):1088-96. PMID: 20588174