combined classical carcinoid and goblet cell carcinoid tumor
Monday 6 September 2010
Carcinoid tumors are the most common neoplasms of the appendix.
Histologically they have been categorized as classical, tubular, or goblet cell types.
Goblet cell carcinoid has been regarded as a distinctive tumor type, not related to classic carcinoids. Combinations of these 2 tumor types have rarely been described. (20631606)
The occurrence of both carcinoid types in the same appendices suggests a closer histogenetic relationship than previously believed, although the possibility that the 2 components represent separate, independent primaries ("collision tumors") can also be considered.
Combined classical carcinoid and goblet cell carcinoid tumor: a new morphologic variant of carcinoid tumor of the appendix. Chetty R, Klimstra DS, Henson DE, Albores-Saavedra J. Am J Surg Pathol. 2010 Aug;34(8):1163-7.PMID: 20631606