bile duct adenoma
Thursday 2 September 2010
Bile duct adenoma
On account of this similarity in phenotype and their frequent close association with a large caliber bile duct, it was earlier suggested that bile duct adenoma represent a peribiliary gland hamartoma.
The distinguishing feature of so-called bile duct adenoma is their display of the same phenotype as pyloric gland metaplasia. They develop as a localized biliary healing response equivalent to the function of a peribiliary gland or pyloric gland metaplasia in the foregut.
Bile Duct Adenoma vs Metastatic PDAC
|Histologic Features||Bile duct adenoma||Metastatic PDAC|
|Angulated glands||Typically Absent||Present|
An Immunohistochemical Profile of the So-called Bile Duct Adenoma: Clues to Pathogenesis. Hughes NR, Goodman ZD, Bhathal PS. Am J Surg Pathol. 2010 Sep;34(9):1312-8. PMID: 20679879