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granulomatous mastitis

Wednesday 21 July 2010

Etiology

- In a case of granulomatous mastitis due to Corynebacterium kroppenstedtii, a strongly impaired neutrophil responses to Nod2 agonist and a single nucleotide polymorphism within the NOD2 gene (SNP13 [Leu1007fsinsC]) in a heterozygous state have been found. These findings provided a demonstration of impaired Nod2 function associated with corynebacterial infection. (#19641059#)

References

- First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria. Bercot B, Kannengiesser C, Oudin C, Grandchamp B, Sanson-le Pors MJ, Mouly S, Elbim C. J Clin Microbiol. 2009 Sep;47(9):3034-7. PMID: #19641059#

- Is granulomatous mastitis a localized form of hidradenitis suppurativa? JOIN-LAMBERT O, FRAITAG S, RIBADEAU-DUMAS F, LEGUERN AS, BEHILLIL S, DEL CASTILLO FJ, CONSIGNY PH, AUQUIER F, EB F, SEVESTRE H, LORTHOLARY O, NASSIF X, NASSIF A. Eur J Dermatol. 2009 Sep-Oct;19(5):513-4. PMID: #19527995#