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filiform polyposis

Friday 30 April 2010

Filiform polyposis is an uncommon entity that is most often encountered in the colon of patients with a history of inflammatory bowel disease (IBD).

Filiform polyposis is characterized by a large number of "wormlike" polyps lined by histologically normal colonic mucosa. These polyps can mimic adenomatous polyps.

Only rare cases without a history or evidence of IBD have been reported.

Differential diagnosis

- neuromuscular and vascular hamartoma (NMVH)

  • The neuromuscular and vascular hamartoma of the small bowel is a rare, focal disorder characterized by disorganized smooth muscle fascicles throughout the submucosa accompanied by fibrosis, nerve fibers, ganglion cells, and vessels.


- Diffuse filiform polyposis with unique histology mimicking familial adenomatous polyposis in a patient without inflammatory bowel disease. Oakley GJ 3rd, Schraut WH, Peel R, Krasinskas A. Arch Pathol Lab Med. 2007 Dec;131(12):1821-4. PMID: 18081442