signet-ring cells

Etiology

 signet-ring cell change

• digestive mucosal injury
  • pseudomembranous colitis

 signet-ring cell tumors

• signet-ring cell carcinomas
• signet-ring cell melanoma
• signet-ring cell lymphoma

Images

 digestive mucosal injury leads to slough of benign mucinous cells. Beware of signet ring cell change in benign polyps, stomach, and pseudomembranous colitis

• https://twitter.com/RhondaYantiss/status/876834829794455552

 Signet-ring Cell Change in pseudomembranous colitis

• https://twitter.com/DraEosina/status/1115990513897934849

 signet-ring cell lymphoma

• https://twitter.com/DrMarkOng/status/1125105400343355394

See also

 signet ring-like cell / signet ring-like cells

References

 Sung CO, Seo JW, Kim KM, Do IG, Kim SW, Park CK. Clinical significance of signet-ring cells in colorectal mucinous adenocarcinoma. Mod Pathol. 2008 Oct 10. PMID: 18849918

 Wang K, Weinrach D, Lal A, Musunuri S, Ramirez J, Ozer O, Keh P, Rao MS. Signet-ring cell change versus signet-ring cell carcinoma: a comparative analysis. Am J Surg Pathol. 2003 Nov;27(11):1429-33.
PMID: 14576475

 Signet-ring cell change versus signet-ring cell carcinoma: a comparative analysis.
Wang K, et al. Am J Surg Pathol. 2003. PMID : 14576475