- Human pathology

Home > D. General pathology > Therapy, Toxics and drugs > MG132


Thursday 22 April 2010

MG132 is a proteasome inhibitor.


- MG132, a proteasome inhibitor, induced death of calf pulmonary artery endothelial cells via caspase-dependent apoptosis and GSH depletion. Han YH, Moon HJ, You BR, Yang YM, Kim SZ, Kim SH, Park WH. Anticancer Res. 2010 Mar;30(3):879-85. PMID: #"20393010#

- MG132, a proteasome inhibitor, attenuates pressure-overload-induced cardiac hypertrophy in rats by modulation of mitogen-activated protein kinase signals. Chen B, Ma Y, Meng R, Xiong Z, Zhang C, Chen G, Zhang A, Dong Y. Acta Biochim Biophys Sin (Shanghai). 2010 Apr;42(4):253-8. PMID: 20383463

- Combination therapy for hepatitis C virus with heat-shock protein 90 inhibitor 17-AAG and proteasome inhibitor MG132. Ujino S, Yamaguchi S, Shimotohno K, Takaku H. Antivir Chem Chemother. 2010 Mar 9;20(4):161-7. PMID: 20231781