Home > E. Pathology by systems > Digestive system > Small intestine > neonatal constitutional diarrhea

neonatal constitutional diarrhea

Thursday 25 March 2010

Types

- congenital chloride diarrhea (DIAR1, MIM.214700, 7q22-q31.1)

  • congenital chloride diarrhea (DIAR1) is caused by mutation in the SLC26A3 gene (MIM.126650) on chromosome 7q31.

- microvillus inclusion disease (DIAR2; MIMI.251850)

  • microvillus inclusion disease is caused by mutation in the MYO5B gene (MIM.606540) on chromosome 18q21

  • - syndromic form of congenital secretory sodium diarrhea (DIAR3, MIM.270420), caused by mutation in the SPINT2 gene (MIM.605124)

- malabsorptive congenital diarrhea (DIAR4; MIM.610370) caused by mutation in the NEUROG3 gene (MIM.604882) on chromosome 10q21.3;

- congenital tufting enteropathy (DIAR5; MIM.613217) caused by mutation in the EPCAM (or TACSTD1) gene (MIM.185535).

See also

- severe diarrhea
- syndromic diarrhea