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RFX6

6q22.31 MIM.612659 HGNC:21478 Entrez:222546

Tuesday 23 February 2010

RFX6 is a winged helix transcription factor expressed almost exclusively in the pancreatic islets. (18673564)

Rfx6 directs islet formation and insulin production in mice and humans. (20148032)

See also

- RFXs

References

- Rfx6 directs islet formation and insulin production in mice and humans. Smith SB, Qu HQ, Taleb N, Kishimoto NY, Scheel DW, Lu Y, Patch AM, Grabs R, Wang J, Lynn FC, Miyatsuka T, Mitchell J, Seerke R, D├ęsir J, Eijnden SV, Abramowicz M, Kacet N, Weill J, Renard ME, Gentile M, Hansen I, Dewar K, Hattersley AT, Wang R, Wilson ME, Johnson JD, Polychronakos C, German MS. Nature. 2010 Feb 11;463(7282):775-80. PMID: 20148032

- Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Soyer J, Flasse L, Raffelsberger W, Beucher A, Orvain C, Peers B, Ravassard P, Vermot J, Voz ML, Mellitzer G, Gradwohl G. Development. 2010 Jan;137(2):203-12. PMID: 20040487

- Identification and characterization of novel human tissue-specific RFX transcription factors. Aftab S, Semenec L, Chu JS, Chen N. BMC Evol Biol. 2008 Aug 1;8:226. PMID: 18673564