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Mulibrey nanism

Monday 25 January 2010

Mulibrey nanism (MUL) is a monogenic disorder with prenatal-onset growth failure, typical clinical characteristics, cardiopathy and tendency for a metabolic syndrome.

Tumoral predisposition (19334051)

- Wilms tumors
- thyroid tumors
- gynecological cancers
- gastrointestinal carcinoid tumor
- Langerhans cell histiocytosis
- acute lymphoblastic leukaemia (ALL)

References

- High frequency of tumours in Mulibrey nanism. Karlberg N, Karlberg S, Karikoski R, Mikkola S, Lipsanen-Nyman M, Jalanko H. J Pathol. 2009 Jun;218(2):163-71. PMID: 19334051