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orbital giant cell fibroblastoma

Wednesday 2 December 2009

Giant cell fibroblastoma, a benign mesenchymal tumor of infancy, is rarely encountered within the orbital region. This lesion is considered to be a distinct, non-metastasizing tumor, but its clinical management may be very difficult, because of its invasive nature and potential for recurrence.

Giant cell fibroblastoma is a phenotypic variant of dermatofibrosarcoma protuberans sharing the same COL1A1/PDGFB fusion gene.

See also

- giant cell fibroblastoma

References

- Orbital giant cell fibroblastoma. Carroll G, Haik BG, Karcioglu ZA. Orbit. 1999 Mar;18(1):25-32. PMID: #12048695#