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angiosarcoma of the scalp and face

Sunday 29 November 2009

Angiosarcoma of the skin is an extremely rare malignant tumor of vascular origin that usually arises in the scalp and face of elderly persons.

Physiopathology

Not only VEGFR-2-mediated signal but also VEGFR-3-mediated signal may contribute to proliferation of vascular tumor cells as autocrine and paracrine signaling factors.

See also

- angiosarcomas

References

- Autocrine and paracrine roles of VEGF/VEGFR-2 and VEGF-C/VEGFR-3 signaling in angiosarcomas of the scalp and face. Tokuyama W, Mikami T, Masuzawa M, Okayasu I. Hum Pathol. 2009 Nov 12. PMID: 19913279