Humpath.com - Human pathology

Home > D. General pathology > Therapy, Toxics and drugs > pazopanib

pazopanib

Tuesday 2 June 2009

Pazopanib is a potent and selective multi-targeted receptor tyrosine kinase inhibitor of VEGFR-1 (VEGFR1), VEGFR-2 (VEGFR2), VEGFR-3 (VGEFR3), PDGFR-a/β (PDGFRA and PDGFRB), and c-kit (KIT) that blocks tumor growth and inhibits angiogenesis.