Home > G. Tumoral pathology > metastasis


Wednesday 29 October 2003

cancer metastasis, tumoral metastasis

Metastasis can be viewed as an evolutionary process, culminating in the prevalence of rare tumour cells that overcame stringent physiological barriers as they separated from their original environment and developmental fate.

This phenomenon brings into focus long-standing questions about the stage at which cancer cells acquire metastatic abilities, the relationship of metastatic cells to their tumour of origin, the basis for metastatic tissue tropism, the nature of metastasis predisposition factors and, importantly, the identity of genes that mediate these processes.


- lymphatic dissemination

  • nodal metastasis
  • carcinomatous lymphangitis

- visceral metastasis

  • pulmonary metastasis
  • hepatic metastasis
  • cerebral metastasis

- osseous metastasis (bone metastasis)
- placental metastasis


- "Identification of metastasis of unknown origin using Cancer Type ID", Jean-Marie Bruey, BioTheranostics, San Diego, CA, USA

< iframe src="http://player.vimeo.com/video/49872638?badge=0" width="500" height="281" frameborder="0" webkitAllowFullScreen mozallowfullscreen allowFullScreen> < /iframe> < p> < a href="http://vimeo.com/49872638">1-6 JEAN-MARIE BRUEY - IDENTIFICATION OF METASTASIS < /a> from < a href="http://vimeo.com/biopathology">Biopathology < /a> on < a href="http://vimeo.com">Vimeo < /a>. < /p>

See also

- circulating tumoral cells
- metastasis of unknow origin


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