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secretory lysosomes

Wednesday 29 October 2003


- lytic granules of cytotoxic T lymphocyte (secretory lysosomes containing both perforin and granzymes)
- melanosomes of melanocytes


- Stinchcombe J, Bossi G, Griffiths GM. Linking albinism and immunity: the secrets of secretory lysosomes. Science. 2004 Jul 2;305(5680):55-9. PMID: 15232098

- Clark R, Griffiths GM. Lytic granules, secretory lysosomes and disease. Curr Opin Immunol. 2003 Oct;15(5):516-21. PMID: 14499259

- Huizing M, Gahl WA. Disorders of vesicles of lysosomal lineage: the Hermansky-Pudlak syndromes. Curr Mol Med. 2002 Aug;2(5):451-67. PMID: 12125811

- Griffiths GM. Albinism and immunity: what’s the link? Curr Mol Med. 2002 Aug;2(5):479-83. PMID: 12125813