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DNA methylation arrays

jeudi 26 mars 2009

Introducing the High-Resolution, High-Sensitivity NimbleGen 2.1M DNA Methylation Arrays

Epigenetic mechanisms, such as DNA methylation, play critical roles in the regulation of gene expression.

Understanding DNA methylation will not only further our knowledge of gene regulation, but given the connection between epigenetics and disease, it will also increase our understanding of disease development hopefully leading to the creation of diagnostics as well as preventative and therapeutic treatment options.

Powerful methods exist to analyze DNA methylation patterns in higher eukaryotes including methylated DNA immunoprecipitation (MeDIP), an affinity based approach to enrich methylated DNA regions from genomic DNA, which can be combined with microarrays to profile genomic DNA methylation patterns.

Assays

- MeDIP-optimized, 2.1M DNA Methylation Array portfolio
- Deluxe Promoter Arrays