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13q loss

Wednesday 15 October 2008

Tumors

- dedifferentiated hepatocellular carcinoma (#18820673#)

  • 6 genes (BIC, CPNE1, RBPMS, RFC4, RPSA, TOP2A) are among the 20 most significantly upregulated genes both in dedifferentiated carcinoma and in carcinoma with loss of 13q. (#18820673#)

References

- Skawran B, Steinemann D, Becker T, Buurman R, Flik J, Wiese B, Flemming P, Kreipe H, Schlegelberger B, Wilkens L. Loss of 13q is associated with genes involved in cell cycle and proliferation in dedifferentiated hepatocellular carcinoma. Mod Pathol. 2008 Sep 26. PMID: #18820673#